Bioinformatics course timetable
June 2017
Tue 27 |
Image Analysis for Biologists
Finished
This course will focus on computational methods for analysing cellular images and extracting quantitative data from them. The aim of this course is to familiarise the participants with computational image analysis methodologies, and to provide hands-on training in running quantitative analysis pipelines. On day 1 we will introduce principles of image processing and analysis, giving an overview of commonly used algorithms through a series of talks and practicals based on Fiji, an extensible open source software package. On day 2, we will describe the open Icy platform developed at the Institut Pasteur. Icy is a next-generation, user-friendly software offering powerful acquisition, visualisation, annotation and analysis algorithms for 5D bioimaging data, together with unique automation/scripting capabilities (notably via its graphical programming interface) and tight integration with existing software (e.g. ImageJ, Matlab, Micro-Manager). On day 3, we will cover time series processing and cell tracking using TrackMate. In the afternoon, we will present the Image Data Resource, an added-value platform that combines data from multiple independent imaging experiments and imaging modalities and integrates them into a single resource for reanalysis in a convenient, scalable form. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book or register your interest by linking here. |
Wed 28 |
Image Analysis for Biologists
Finished
This course will focus on computational methods for analysing cellular images and extracting quantitative data from them. The aim of this course is to familiarise the participants with computational image analysis methodologies, and to provide hands-on training in running quantitative analysis pipelines. On day 1 we will introduce principles of image processing and analysis, giving an overview of commonly used algorithms through a series of talks and practicals based on Fiji, an extensible open source software package. On day 2, we will describe the open Icy platform developed at the Institut Pasteur. Icy is a next-generation, user-friendly software offering powerful acquisition, visualisation, annotation and analysis algorithms for 5D bioimaging data, together with unique automation/scripting capabilities (notably via its graphical programming interface) and tight integration with existing software (e.g. ImageJ, Matlab, Micro-Manager). On day 3, we will cover time series processing and cell tracking using TrackMate. In the afternoon, we will present the Image Data Resource, an added-value platform that combines data from multiple independent imaging experiments and imaging modalities and integrates them into a single resource for reanalysis in a convenient, scalable form. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book or register your interest by linking here. |
July 2017
Mon 3 |
This event will consist of two parts. The first part of the workshop aims to provide new trainers with guidance and tips for developing and delivering training in bioinformatics, exploring a range of methods appropriate to different learning styles and examining the requirements for a successful course (both scientific and logistic). It will be based on the EXCELERATE Train-the-Trainer (TtT) course materials and content will be tailored to trainers that are involved in teaching bioinformatics to clinical audiences. The second part of the workshop will focus on "Best practices in clinical bioinformatics training", providing an opportunity for people already involved in this kind of training, or in the process of developing it, to come together and exchange best practice/experiences. Participants will include training providers of the Health Education England’s MSc in Genomics Medicine from several UK Universities as well as other providers active in this area, from around Europe and beyond. This event is co-sponsored by ELIXIR-EXCELERATE and Health Education England (HEE). |
Tue 4 |
This event will consist of two parts. The first part of the workshop aims to provide new trainers with guidance and tips for developing and delivering training in bioinformatics, exploring a range of methods appropriate to different learning styles and examining the requirements for a successful course (both scientific and logistic). It will be based on the EXCELERATE Train-the-Trainer (TtT) course materials and content will be tailored to trainers that are involved in teaching bioinformatics to clinical audiences. The second part of the workshop will focus on "Best practices in clinical bioinformatics training", providing an opportunity for people already involved in this kind of training, or in the process of developing it, to come together and exchange best practice/experiences. Participants will include training providers of the Health Education England’s MSc in Genomics Medicine from several UK Universities as well as other providers active in this area, from around Europe and beyond. This event is co-sponsored by ELIXIR-EXCELERATE and Health Education England (HEE). |
Wed 5 |
This event will consist of two parts. The first part of the workshop aims to provide new trainers with guidance and tips for developing and delivering training in bioinformatics, exploring a range of methods appropriate to different learning styles and examining the requirements for a successful course (both scientific and logistic). It will be based on the EXCELERATE Train-the-Trainer (TtT) course materials and content will be tailored to trainers that are involved in teaching bioinformatics to clinical audiences. The second part of the workshop will focus on "Best practices in clinical bioinformatics training", providing an opportunity for people already involved in this kind of training, or in the process of developing it, to come together and exchange best practice/experiences. Participants will include training providers of the Health Education England’s MSc in Genomics Medicine from several UK Universities as well as other providers active in this area, from around Europe and beyond. This event is co-sponsored by ELIXIR-EXCELERATE and Health Education England (HEE). |
Mon 10 |
Protein Structure Analysis
Finished
This course covers data resources and analytical approaches for the discovery and interpretation of biomacromolecular structures. Day 1 focuses on public repositories of structural data (Protein Data Bank and Electron Microscopy Data Bank) and resources for protein analysis and classification (Pfam, InterPro and HMMER). Day 2 covers how to find information about the structure and function of your protein sequence using CATH, principles of modern state-of-the-art protein modelling with Phyre2 and methods for predicting the effects of mutations on protein structure and function using the SAAP family of tools. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |
Tue 11 |
Protein Structure Analysis
Finished
This course covers data resources and analytical approaches for the discovery and interpretation of biomacromolecular structures. Day 1 focuses on public repositories of structural data (Protein Data Bank and Electron Microscopy Data Bank) and resources for protein analysis and classification (Pfam, InterPro and HMMER). Day 2 covers how to find information about the structure and function of your protein sequence using CATH, principles of modern state-of-the-art protein modelling with Phyre2 and methods for predicting the effects of mutations on protein structure and function using the SAAP family of tools. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |
Wed 12 |
Variant Analysis with GATK
Finished
This workshop will focus on the core steps involved in calling variants with the Broad’s Genome Analysis Toolkit, using the “Best Practices” developed by the GATK team. You will learn why each step is essential to the variant discovery process, what are the operations performed on the data at each step, and how to use the GATK tools to get the most accurate and reliable results out of your dataset. In the course of this workshop, we highlight key functionalities such as the germline GVCF workflow for joint variant discovery in cohorts, RNAseq specific processing, and somatic variant discovery using MuTect2. We also preview capabilities of the upcoming GATK version 4, including a new workflow for CNV discovery, and we demonstrate the use of pipelining tools to assemble and execute GATK workflows. The workshop is composed of one day of lectures and two days of handson training, structured as follows. Day 1: theory and application of the Best Practices for Variant Discovery in highthroughput sequencing data. Day 2 and the morning of Day 3: handson exercises on how to manipulate the standard data formats involved in variant discovery and how to apply GATK tools appropriately to various use cases and data types. Day 3 afternoon: hands-on exercises on how to write workflow scripts using WDL, the Broad's new Workflow Description Language, and to execute these workflows locally as well as through a publicly accessible cloud-based service. Please note that this workshop is focused on human data analysis. The majority of the materials presented does apply equally to nonhuman data, and we will address some questions regarding adaptations that are needed for analysis of non-human data, but we will not go into much detail on those points. Please note that if you are not eligible for a University of Cambridge Raven account you will need to Book or register Interest by linking here. |
How much data would you lose if your laptop was stolen? Have you ever emailed your colleague a file named 'final_final_versionEDITED'? Have you ever struggled to import your spreadsheets into R? As a researcher, you will encounter research data in many forms, ranging from measurements, numbers and images to documents and publications. Whether you create, receive or collect data, you will certainly need to organise it at some stage of your project. This workshop will provide an overview of some basic principles on how we can work with data more effectively. We will discuss the best practices for research data management and organisation so that our research is auditable and reproducible by ourselves, and others, in the future. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book or register your interest by linking here. |
|
Thu 13 |
Variant Analysis with GATK
Finished
This workshop will focus on the core steps involved in calling variants with the Broad’s Genome Analysis Toolkit, using the “Best Practices” developed by the GATK team. You will learn why each step is essential to the variant discovery process, what are the operations performed on the data at each step, and how to use the GATK tools to get the most accurate and reliable results out of your dataset. In the course of this workshop, we highlight key functionalities such as the germline GVCF workflow for joint variant discovery in cohorts, RNAseq specific processing, and somatic variant discovery using MuTect2. We also preview capabilities of the upcoming GATK version 4, including a new workflow for CNV discovery, and we demonstrate the use of pipelining tools to assemble and execute GATK workflows. The workshop is composed of one day of lectures and two days of handson training, structured as follows. Day 1: theory and application of the Best Practices for Variant Discovery in highthroughput sequencing data. Day 2 and the morning of Day 3: handson exercises on how to manipulate the standard data formats involved in variant discovery and how to apply GATK tools appropriately to various use cases and data types. Day 3 afternoon: hands-on exercises on how to write workflow scripts using WDL, the Broad's new Workflow Description Language, and to execute these workflows locally as well as through a publicly accessible cloud-based service. Please note that this workshop is focused on human data analysis. The majority of the materials presented does apply equally to nonhuman data, and we will address some questions regarding adaptations that are needed for analysis of non-human data, but we will not go into much detail on those points. Please note that if you are not eligible for a University of Cambridge Raven account you will need to Book or register Interest by linking here. |
Fri 14 |
Variant Analysis with GATK
Finished
This workshop will focus on the core steps involved in calling variants with the Broad’s Genome Analysis Toolkit, using the “Best Practices” developed by the GATK team. You will learn why each step is essential to the variant discovery process, what are the operations performed on the data at each step, and how to use the GATK tools to get the most accurate and reliable results out of your dataset. In the course of this workshop, we highlight key functionalities such as the germline GVCF workflow for joint variant discovery in cohorts, RNAseq specific processing, and somatic variant discovery using MuTect2. We also preview capabilities of the upcoming GATK version 4, including a new workflow for CNV discovery, and we demonstrate the use of pipelining tools to assemble and execute GATK workflows. The workshop is composed of one day of lectures and two days of handson training, structured as follows. Day 1: theory and application of the Best Practices for Variant Discovery in highthroughput sequencing data. Day 2 and the morning of Day 3: handson exercises on how to manipulate the standard data formats involved in variant discovery and how to apply GATK tools appropriately to various use cases and data types. Day 3 afternoon: hands-on exercises on how to write workflow scripts using WDL, the Broad's new Workflow Description Language, and to execute these workflows locally as well as through a publicly accessible cloud-based service. Please note that this workshop is focused on human data analysis. The majority of the materials presented does apply equally to nonhuman data, and we will address some questions regarding adaptations that are needed for analysis of non-human data, but we will not go into much detail on those points. Please note that if you are not eligible for a University of Cambridge Raven account you will need to Book or register Interest by linking here. |
Wed 19 |
|
Mon 24 |
CRUK Summer School
Finished
CRUK Summer School Event posted for Administration purposes only |
Tue 25 |
CRUK Summer School
Finished
CRUK Summer School Event posted for Administration purposes only |
Wed 26 |
CRUK Summer School
Finished
CRUK Summer School Event posted for Administration purposes only |
Thu 27 |
CRUK Summer School
Finished
CRUK Summer School Event posted for Administration purposes only |
Fri 28 |
CRUK Summer School
Finished
CRUK Summer School Event posted for Administration purposes only |
August 2017
Wed 30 |
Basic statistics and data handling
Finished
This three day course is intended to open doors to applying statistics - whether directly increasing skills and personally undertaking analyses, or by expanding knowledge towards identifying collaborators. The end goal is to drive confident engagement with data analysis and further training - increasing the quality and reliability of interpretation, and putting that interpretation and subsequent presentation into the hands of the researcher. Each day of the course will deliver a mixture of lectures, workshops and hands-on practicals – and will focus on the following specific elements. Day 1 focuses on basic approaches and the computer skills required to do downstream analysis. Covering: Basic skills for data manipulation in R. How to prepare your data effectively. Principles of experimental design and how this influences analysis. On day 2, participants will explore the core concepts of statistics – so that they can begin to see how they can be applied to their own work, and to also help with better critical evaluation of the work of others. Covering: Basic statistics concepts and practice: power, variability, false discovery, t-test, effect size, simulations to understand what a p-value means. On day 3 we will continue to explore core concepts of statistics, focusing on linear regression and multiple testing correction. Course materials are available here. This event is supported by the BBSRC Strategic Training Awards for Research Skills (STARS) grant (BB/P022766/1). Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |
Thu 31 |
Basic statistics and data handling
Finished
This three day course is intended to open doors to applying statistics - whether directly increasing skills and personally undertaking analyses, or by expanding knowledge towards identifying collaborators. The end goal is to drive confident engagement with data analysis and further training - increasing the quality and reliability of interpretation, and putting that interpretation and subsequent presentation into the hands of the researcher. Each day of the course will deliver a mixture of lectures, workshops and hands-on practicals – and will focus on the following specific elements. Day 1 focuses on basic approaches and the computer skills required to do downstream analysis. Covering: Basic skills for data manipulation in R. How to prepare your data effectively. Principles of experimental design and how this influences analysis. On day 2, participants will explore the core concepts of statistics – so that they can begin to see how they can be applied to their own work, and to also help with better critical evaluation of the work of others. Covering: Basic statistics concepts and practice: power, variability, false discovery, t-test, effect size, simulations to understand what a p-value means. On day 3 we will continue to explore core concepts of statistics, focusing on linear regression and multiple testing correction. Course materials are available here. This event is supported by the BBSRC Strategic Training Awards for Research Skills (STARS) grant (BB/P022766/1). Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |
September 2017
Fri 1 |
Basic statistics and data handling
Finished
This three day course is intended to open doors to applying statistics - whether directly increasing skills and personally undertaking analyses, or by expanding knowledge towards identifying collaborators. The end goal is to drive confident engagement with data analysis and further training - increasing the quality and reliability of interpretation, and putting that interpretation and subsequent presentation into the hands of the researcher. Each day of the course will deliver a mixture of lectures, workshops and hands-on practicals – and will focus on the following specific elements. Day 1 focuses on basic approaches and the computer skills required to do downstream analysis. Covering: Basic skills for data manipulation in R. How to prepare your data effectively. Principles of experimental design and how this influences analysis. On day 2, participants will explore the core concepts of statistics – so that they can begin to see how they can be applied to their own work, and to also help with better critical evaluation of the work of others. Covering: Basic statistics concepts and practice: power, variability, false discovery, t-test, effect size, simulations to understand what a p-value means. On day 3 we will continue to explore core concepts of statistics, focusing on linear regression and multiple testing correction. Course materials are available here. This event is supported by the BBSRC Strategic Training Awards for Research Skills (STARS) grant (BB/P022766/1). Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |
Mon 4 |
R is a highly-regarded, free, software environment for statistical analysis, with many useful features that promote and facilitate reproducible research. In this course, we give an introduction to the R environment and explain how it can be used to import, manipulate and analyse tabular data. After the course you should feel confident to start exploring your own dataset using the materials and references provided. The course website providing links to the course materials is here. Please note that although we will demonstrate how to perform statistical analysis in R, we will not cover the theory of statistical analysis in this course. Those seeking an in-depth explanation of how to perform and interpret statistical tests are advised to see the list of Related courses. Moreover, those with some programming experience in other languages (e.g. Python, Perl) might wish to attend the follow-on Data Analysis and Visualisation in R course. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book or register your interest by linking here. |
Tue 5 |
R is a highly-regarded, free, software environment for statistical analysis, with many useful features that promote and facilitate reproducible research. In this course, we give an introduction to the R environment and explain how it can be used to import, manipulate and analyse tabular data. After the course you should feel confident to start exploring your own dataset using the materials and references provided. The course website providing links to the course materials is here. Please note that although we will demonstrate how to perform statistical analysis in R, we will not cover the theory of statistical analysis in this course. Those seeking an in-depth explanation of how to perform and interpret statistical tests are advised to see the list of Related courses. Moreover, those with some programming experience in other languages (e.g. Python, Perl) might wish to attend the follow-on Data Analysis and Visualisation in R course. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book or register your interest by linking here. |
Wed 6 |
Data Analysis and Visualisation in R
Finished
This course introduces some relatively new additions to the R programming language: dplyr and ggplot2. In combination these R packages provide a powerful toolkit to make the process of manipulating and visualising data easy and intuitive. Materials for this course can be found here. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |
Fri 8 |
Using the Ensembl Genome Browser
Finished
The Ensembl Project provides a comprehensive and integrated source of annotation of, mainly vertebrate, genome sequences. This workshop offers a comprehensive practical introduction to the use of the Ensembl genome browser as well as essential background information. This course will focus on the vertebrate genomes in Ensembl, however much of what will be covered is also applicable to the non-vertebrates (plants, bacteria, fungi, metazoa and protists) in Ensembl Genomes. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book or register your interest by linking here. |
Mon 11 |
Data Carpentry
Finished
In many domains of research the rapid generation of large amounts of data is fundamentally changing how research is done. The deluge of data presents great opportunities, but also many challenges in managing, analyzing and sharing data. Data Carpentry workshops are designed to teach basic concepts, skills and tools for working more effectively with data. The workshop is aimed at researchers in the life sciences at all career stages and is designed for learners with little to no prior knowledge of programming, shell scripting, or command line tools. Course materials can be found here. This course is organized in collaboration with ElixirUK and the Software Sustainability Institute. Please note that if you are not eligible for a University of Cambridge Raven account you will need to book by linking here. |