Chemistry: DD4 Pharmacokinetics

Updated

Predicting and controlling how a chemical molecule will be processed by the body is vital to developing a successful drug. This lecture will discuss the path a molecule takes from initial dose through to elimination, describe the ADME (Absorption, Distribution, Metabolism and Excretion) processes that take place and how these are related to compound structure and physicochemical properties. In addition to standard small molecule PK some other new modalities will be also be introduced to illustrate how methods such as PEGylation and lipoparticle encapsulation can be employed to modulate compound pharmacokinetic properties.

• Chemistry postgraduates
• Further details regarding eligibility criteria are available
• If you are from outside the Department of Chemistry, please wait to be collected from reception

Number of sessions: 1

• One session of one hour

• Chemistry: DD1 The Drug Discovery Process
• Chemistry: DD2 The Drug Discovery Process
• Chemistry: DD3 Modern Tactics to Optimise Potency
• Chemistry: DD5 Medicinal Chemistry Game Workshop
• Chemistry: DD6 Toxicity and Drug Safety
• Chemistry: DD7 Kinase Inhibitor Case Studies